ALX4 antibody

Catalog No. ABIN2716017

Product Details anti-ALX4 Antibody

Target: ALX4 (ALX Homeobox 4 (ALX4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALX4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Characteristics: Homo sapiens ALX homeobox 4 (ALX4)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ALX4(NP_068745) produced in HEK293T cell.

Clone: 2F2

Isotype: IgG1

Application Details

Application Notes: WB 1:1000, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ALX4

Target: ALX4 (ALX Homeobox 4 (ALX4))

Alternative Name: ALX4 (ALX4 Products)

Background: This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

Molecular Weight: 44.1 kDa

Gene ID: 60529

NCBI Accession: NM_021926

HGNC: 60529