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ARID1A antibody (N-Term)
ARID1A
Reactivity: Human, Mouse, Rat
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ARID1A Antibody
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Target
See all ARID1A Antibodies
ARID1A
(AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
Binding Specificity
All epitopes for ARID1A antibodies
N-Term
Reactivity
All reactivities for ARID1A antibodies
Human, Mouse, Rat
Host
All hosts for ARID1A antibodies
Rabbit
Clonality
All clonalities for ARID1A antibodies
Polyclonal
Conjugate
All conjugates for ARID1A antibodies
This ARID1A antibody is un-conjugated
Application
All applications for ARID1A antibodies
ELISA, Western Blotting (WB)
Specificity
ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
Purification
ARID1A antibody is affinity chromatography purified via peptide column.
Immunogen
ARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A.
Isotype
IgG
Top Product
Discover our top product ARID1A Primary Antibody
Alternatives
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Application Details
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Application Notes
ARID1A antibody can be used for detection of ARID1A by Western blot at 1 - 2 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Can be stored at 4 °C for three months and -20 °C, stable for up to one year.
Target Details for ARID1A
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Target
ARID1A
(AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
Alternative Name
ARID1A (ARID1A Products )
Synonyms
B120 antibody, BAF250 antibody, BAF250a antibody, BM029 antibody, C1orf4 antibody, ELD antibody, MRD14 antibody, OSA1 antibody, P270 antibody, SMARCF1 antibody, hELD antibody, hOSA1 antibody, 1110030E03Rik antibody, Osa1 antibody, Smarcf1 antibody, ARID1A antibody, wu:fb79b07 antibody, wu:fb95g08 antibody, zgc:171438 antibody, AT-rich interaction domain 1A antibody, AT rich interactive domain 1A (SWI-like) antibody, AT rich interactive domain 1Aa (SWI-like) antibody, ARID1A antibody, Arid1a antibody, arid1a antibody, arid1aa antibody
Background
The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).
Molecular Weight
Predicted: 133, 227, 251 kDa Observed: 130, 260 kDa
Gene ID
8289
NCBI Accession
NP_006006
UniProt
O14497
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Tube Formation
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