TUT1 antibody

Catalog No. ABIN2458014

Product Details anti-TUT1 Antibody

Target: TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TUT1.

Application Details

Application Notes: TUT1 antibody can be used for detection of TUT1 by ELISA at 1:1562500. TUT1 antibody can be used for detection of TUT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TUT1 antibody at -20 °C.

Target Details for TUT1

Target: TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))

Alternative Name: TUT1 (TUT1 Products)

Synonyms: PAPD2 antibody, RBM21 antibody, STARPAP antibody, TUTase antibody, 2700038E08Rik antibody, Rbm21 antibody, zgc:112254 antibody, terminal uridylyl transferase 1, U6 snRNA-specific antibody, TUT1 antibody, Tut1 antibody, tut1 antibody

Background: TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6, MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).

Molecular Weight: 94 kDa

Gene ID: 64852

NCBI Accession: NP_073741

UniProt: A8K995