GABRA5 antibody

Catalog No. ABIN2458125

Product Details anti-GABRA5 Antibody

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRA5.

Application Details

Application Notes: GABRA5 antibody can be used for detection of GABRA5 by ELISA at 1:312500. GABRA5 antibody can be used for detection of GABRA5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GABRA5 antibody at -20 °C.

Target Details for GABRA5

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Alternative Name: GABRA5 (GABRA5 Products)

Synonyms: GABRA5 antibody, si:dkey-93p24.1 antibody, A230018I05Rik antibody, gamma-aminobutyric acid type A receptor alpha5 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 5 antibody, gamma-aminobutyric acid type A receptor alpha 5 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 antibody, gamma-aminobutyric acid receptor subunit alpha-5 antibody, GABRA5 antibody, gabra5 antibody, Gabra5 antibody, LOC100653497 antibody

Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 49 kDa

Gene ID: 2558

NCBI Accession: NP_000801

UniProt: P31644

Pathways: Sensory Perception of Sound, Synaptic Membrane