SCN1B antibody

Catalog No. ABIN2458126

Product Details anti-SCN1B Antibody

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCN1B.

Application Details

Application Notes: SCN1B antibody can be used for detection of SCN1B by ELISA at 1:62500. SCN1B antibody can be used for detection of SCN1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SCN1B antibody at -20 °C.

Target Details for SCN1B

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Alternative Name: SCN1B (SCN1B Products)

Synonyms: GEFSP1 antibody, sodium channel, voltage-gated, type I, beta antibody, sodium voltage-gated channel beta subunit 1 antibody, Scn1b antibody, SCN1B antibody

Background: Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.

Molecular Weight: 25 kDa

Gene ID: 6324

NCBI Accession: NP_001028

UniProt: Q07699