HTR3E antibody

Catalog No. ABIN2458154

Product Details anti-HTR3E Antibody

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3E antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3E.

Application Details

Application Notes: HTR3E antibody can be used for detection of HTR3E by ELISA at 1:312500. HTR3E antibody can be used for detection of HTR3E by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HTR3E antibody at -20 °C.

Target Details for HTR3E

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Alternative Name: HTR3E (HTR3E Products)

Synonyms: 5-HT3-E antibody, 5-HT3E antibody, 5-HT3c1 antibody, 5-hydroxytryptamine receptor 3E antibody, HTR3E antibody

Background: HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

Molecular Weight: 53 kDa

Gene ID: 285242

NCBI Accession: NP_872395

UniProt: A5X5Y0