VSX1 antibody

Catalog No. ABIN2458182

Product Details anti-VSX1 Antibody

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VSX1.

Application Details

Application Notes: VSX1 antibody can be used for detection of VSX1 by ELISA at 1:62500. VSX1 antibody can be used for detection of VSX1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store VSX1 antibody at -20 °C.

Target Details for VSX1

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Alternative Name: VSX1 (VSX1 Products)

Synonyms: VSX1 antibody, CAASDS antibody, KTCN antibody, KTCN1 antibody, PPCD antibody, PPD antibody, RINX antibody, CHX10-1 antibody, CHX10-like antibody, visual system homeobox 1 antibody, visual system homeobox 1 L homeolog antibody, visual system homeobox 1 homolog, chx10-like antibody, Vsx1 antibody, VSX1 antibody, Tsp_01485 antibody, vsx1.L antibody, vsx1 antibody

Background: VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in VSX1 can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 38 kDa

Gene ID: 30813

NCBI Accession: NP_055403

UniProt: Q9NZR4