HOXB8 antibody

Catalog No. ABIN2458202

Product Details anti-HOXB8 Antibody

Target: HOXB8 (Homeobox B8 (HOXB8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXB8.

Application Details

Application Notes: HOXB8 antibody can be used for detection of HOXB8 by ELISA at 1:312500. HOXB8 antibody can be used for detection of HOXB8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HOXB8 antibody at -20 °C.

Target Details for HOXB8

Target: HOXB8 (Homeobox B8 (HOXB8))

Alternative Name: HOXB8 (HOXB8 Products)

Synonyms: HOX2 antibody, HOX2D antibody, Hox-2.4 antibody, Hox2r1a antibody, hoxa8 antibody, z-9 antibody, HBX antibody, HBX24 antibody, HOXB8 antibody, homeobox B8 antibody, homeobox protein Hox-B8 antibody, homeo box B8 antibody, homeobox B8b antibody, porcine homeobox antibody, HOXB8 antibody, Hoxb8 antibody, LOC785855 antibody, hoxb8b antibody, HOX-2.4 antibody

Background: HOXB8 belongs to the Antp homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. This gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Molecular Weight: 27 kDa

Gene ID: 3218

NCBI Accession: NP_076921

UniProt: P17481