AHRR antibody

Catalog No. ABIN2458399

Product Details anti-AHRR Antibody

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHRR antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AHRR.

Application Details

Application Notes: AHRR antibody can be used for detection of AHRR by ELISA at 1:312500. AHRR antibody can be used for detection of AHRR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AHRR antibody at -20 °C.

Target Details for AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Alternative Name: AHRR (AHRR Products)

Synonyms: mKIAA1234 antibody, AHH antibody, AHHR antibody, bHLHe77 antibody, ahh antibody, ahhr antibody, bhlhe77 antibody, ahrr2 antibody, aryl-hydrocarbon receptor repressor antibody, aryl hydrocarbon receptor repressor-like antibody, uncharacterized LOC723045 antibody, aryl-hydrocarbon receptor repressor L homeolog antibody, aryl hydrocarbon receptor repressor antibody, aryl-hydrocarbon receptor repressor b antibody, Ahrr antibody, AHRR antibody, LOC529500 antibody, LOC723045 antibody, ahrr.L antibody, LOC100455869 antibody, ahrr antibody, LOC100136487 antibody, ahrrb antibody

Background: Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 78 kDa

Gene ID: 57491

NCBI Accession: NP_065782

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha