SSX5 antibody

Catalog No. ABIN2458407

Product Details anti-SSX5 Antibody

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SSX5.

Application Details

Application Notes: SSX5 antibody can be used for detection of SSX5 by ELISA at 1:62500. SSX5 antibody can be used for detection of SSX5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SSX5 antibody at -20 °C.

Target Details for SSX5

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Alternative Name: SSX5 (SSX5 Products)

Synonyms: putative protein SSX6 antibody, synovial sarcoma, X breakpoint 5 antibody, SSX family member 5 antibody, LOC612524 antibody, SSX5 antibody

Background: SSX5 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X,18) translocation characteristically found in all synovial sarcomas. The gene encoding SSX5 appears not to be involved in this type of chromosome translocation. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 26 kDa

Gene ID: 6758

NCBI Accession: NP_066295

UniProt: Q5JQ60