MSL3 antibody

Catalog No. ABIN2458439

Product Details anti-MSL3 Antibody

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSL3L1.

Application Details

Application Notes: MSL3L1 antibody can be used for detection of MSL3L1 by ELISA at 1:62500. MSL3L1 antibody can be used for detection of MSL3L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MSL3L1 antibody at -20 °C.

Target Details for MSL3

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Alternative Name: MSL3L1 (MSL3 Products)

Synonyms: MSL3 antibody, MSL3L1 antibody, msl3l1 antibody, AU018931 antibody, Msl31 antibody, Msl3l1 antibody, male-specific lethal 3 homolog (Drosophila) antibody, MSL complex subunit 3 antibody, MSL complex subunit 3 L homeolog antibody, MSL3 antibody, msl3 antibody, msl3.L antibody, Msl3 antibody

Background: MSL3L1 is a nuclear protein, which is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

Molecular Weight: 60 kDa

Gene ID: 10943

NCBI Accession: NP_523353

UniProt: Q8N5Y2