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INSIG2 antibody

INSIG2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2458474
  • Target See all INSIG2 Antibodies
    INSIG2 (Insulin Induced Gene 2 (INSIG2))
    Reactivity
    • 21
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INSIG2 antibody is un-conjugated
    Application
    • 22
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INSIG2.
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    Discover our top product INSIG2 Primary Antibody
  • Application Notes
    INSIG2 antibody can be used for detection of INSIG2 by ELISA at 1:62500. INSIG2 antibody can be used for detection of INSIG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store INSIG2 antibody at -20 °C.
  • Target
    INSIG2 (Insulin Induced Gene 2 (INSIG2))
    Alternative Name
    INSIG2 (INSIG2 Products)
    Synonyms
    MGC82156 antibody, INSIG-2 antibody, 2900053I11Rik antibody, C730043J18Rik antibody, Insig-2 antibody, insulin induced gene 2 antibody, insulin induced gene 2 L homeolog antibody, insig2 antibody, insig2.L antibody, INSIG2 antibody, Insig2 antibody
    Background
    INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Molecular Weight
    25 kDa
    Gene ID
    51141
    NCBI Accession
    NP_057217
    UniProt
    Q9Y5U4
    Pathways
    ER-Nucleus Signaling
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