CARS antibody

Catalog No. ABIN2458484

Product Details anti-CARS Antibody

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CARS.

Application Details

Application Notes: CARS antibody can be used for detection of CARS by ELISA at 1:1562500. CARS antibody can be used for detection of CARS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CARS antibody at -20 °C.

Target Details for CARS

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Alternative Name: CARS (CARS Products)

Synonyms: sb:cb71 antibody, CARS antibody, BcDNA:LD21177 antibody, CG8431 antibody, CRS antibody, CysRS antibody, Dmel\\CG8431 antibody, BA0089 antibody, DDBDRAFT_0215191 antibody, DDBDRAFT_0231320 antibody, DDB_0215191 antibody, DDB_0231320 antibody, DDBDRAFT_0187313 antibody, DDBDRAFT_0231318 antibody, DDB_0187313 antibody, DDB_0231318 antibody, T16B12.16 antibody, K15E6.3 antibody, K15E6_3 antibody, CARS1 antibody, CYSRS antibody, MGC:11246 antibody, CA3 antibody, cysteinyl-tRNA synthetase antibody, Cysteinyl-tRNA synthetase antibody, cysteine--tRNA ligase antibody, cysteine-tRNA ligase antibody, Cysteinyl-tRNA synthetase, class Ia family protein antibody, cysteinyl-tRNA synthetase CysS antibody, cysteinyl-tRNA synthetase S homeolog antibody, CARS antibody, cars antibody, CysRS antibody, cysS antibody, APH_RS02395 antibody, mcysS antibody, SYCO ARATH antibody, AT3G56300 antibody, AT5G38830 antibody, cars.S antibody, Cars antibody

Background: CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 95 kDa

Gene ID: 833

NCBI Accession: NP_001014437

UniProt: P49589