PABP antibody

Catalog No. ABIN2458492

Product Details anti-PABP Antibody

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PABP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PABPC1.

Application Details

Application Notes: PABPC1 antibody can be used for detection of PABPC1 by ELISA at 1:1562500. PABPC1 antibody can be used for detection of PABPC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PABPC1 antibody at -20 °C.

Target Details for PABP

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Alternative Name: PABPC1 (PABPC1 Products)

Synonyms: PAB1 antibody, PABP antibody, PABP1 antibody, PABPC2 antibody, PABPL1 antibody, Pabp1 antibody, PabpI antibody, Pabpl1 antibody, ePAB antibody, Pabp antibody, pab1 antibody, pabp antibody, pabp1 antibody, pabpc1 antibody, pabpc2 antibody, PABPC1 antibody, wu:fb16a02 antibody, wu:fi19b08 antibody, wu:fj12d09 antibody, wu:fj61f06 antibody, zgc:109879 antibody, zgc:77608 antibody, poly(A) binding protein cytoplasmic 1 antibody, poly(A) binding protein, cytoplasmic 1 antibody, poly(A) binding protein, cytoplasmic 1 S homeolog antibody, poly(A) binding protein cytoplasmic 1 like antibody, poly(A) binding protein, cytoplasmic 1 L homeolog antibody, poly(A) binding protein, cytoplasmic 1a antibody, poly A binding protein, cytoplasmic 1 b antibody, PABPC1 antibody, Pabpc1 antibody, pabpc1.S antibody, pabpc1 antibody, PABPC1L antibody, pabpc1.L antibody, pabpc1a antibody, pabpc1b antibody

Background: The poly (A)-binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly (A)-binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.

Molecular Weight: 71 kDa

Gene ID: 26986

NCBI Accession: NP_002559

UniProt: P11940

Pathways: SARS-CoV-2 Protein Interactome