SMNDC1 antibody

Catalog No. ABIN2458518

Product Details anti-SMNDC1 Antibody

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMNDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMNDC1.

Application Details

Application Notes: SMNDC1 antibody can be used for detection of SMNDC1 by ELISA at 1:1562500. SMNDC1 antibody can be used for detection of SMNDC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMNDC1 antibody at -20 °C.

Target Details for SMNDC1

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Alternative Name: SMNDC1 (SMNDC1 Products)

Synonyms: smnr antibody, spf30 antibody, SMNDC1 antibody, SMNR antibody, SPF30 antibody, TDRD16C antibody, wu:fb37h07 antibody, wu:fc23a07 antibody, 2410004J23Rik antibody, 4933440I19Rik antibody, survival motor neuron domain containing 1 antibody, smndc1 antibody, SMNDC1 antibody, Bm1_41545 antibody, Smndc1 antibody

Background: This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.

Molecular Weight: 27 kDa

Gene ID: 10285

NCBI Accession: NP_005862

UniProt: O75940