WDR4 antibody

Catalog No. ABIN2458574

Product Details anti-WDR4 Antibody

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR4.

Application Details

Application Notes: WDR4 antibody can be used for detection of WDR4 by ELISA at 1:62500. WDR4 antibody can be used for detection of WDR4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WDR4 antibody at -20 °C.

Target Details for WDR4

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Alternative Name: WDR4 (WDR4 Products)

Synonyms: TRM82 antibody, TRMT82 antibody, AI415180 antibody, AI448349 antibody, D530049K22Rik antibody, WD repeat domain 4 antibody, WD repeat domain 4 S homeolog antibody, WDR4 antibody, Wdr4 antibody, wdr4.S antibody

Background: WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 45 kDa

Gene ID: 10785

NCBI Accession: NP_061139

UniProt: P57081