CSHL1 antibody

Catalog No. ABIN2458618

Product Details anti-CSHL1 Antibody

Target: CSHL1 (Chorionic Somatomammotropin Hormone-Like 1 (CSHL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSHL1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSHL1.

Application Details

Application Notes: CSHL1 antibody can be used for detection of CSHL1 by ELISA at 1:62500. CSHL1 antibody can be used for detection of CSHL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CSHL1 antibody at -20 °C.

Target Details for CSHL1

Target: CSHL1 (Chorionic Somatomammotropin Hormone-Like 1 (CSHL1))

Alternative Name: CSHL1 (CSHL1 Products)

Synonyms: CSHL1 antibody, PL-D antibody, CS-5 antibody, CSHP1 antibody, CSL antibody, hCS-L antibody, placental lactogen PL-D antibody, chorionic somatomammotropin hormone like 1 antibody, PL-D antibody, CSHL1 antibody

Background: CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 20 kDa

Gene ID: 1444

NCBI Accession: NP_072103

UniProt: Q14406