RHCE antibody

Catalog No. ABIN2458666

Product Details anti-RHCE Antibody

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHCE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RHCE.

Application Details

Application Notes: RHCE antibody can be used for detection of RHCE by ELISA at 1:62500. RHCE antibody can be used for detection of RHCE by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RHCE antibody at -20 °C.

Target Details for RHCE

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Alternative Name: RHCE (RHCE Products)

Synonyms: CD240CE antibody, RH antibody, RH30A antibody, RHC antibody, RHE antibody, RHIXB antibody, RHPI antibody, Rh4 antibody, RhIVb(J) antibody, RhVI antibody, RhVIII antibody, RHCE antibody, Rh blood group CcEe antigens antibody, Rh blood group, CcEe antigens antibody, RHCE antibody

Background: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease.The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms.

Molecular Weight: 29 kDa

Gene ID: 6006

NCBI Accession: NP_619522

UniProt: P18577