ATG4A antibody

Catalog No. ABIN2458681

Product Details anti-ATG4A Antibody

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATG4A.

Application Details

Application Notes: ATG4A antibody can be used for detection of ATG4A by ELISA at 1:312500. ATG4A antibody can be used for detection of ATG4A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATG4A antibody at -20 °C.

Target Details for ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Alternative Name: ATG4A (ATG4A Products)

Synonyms: apg4a antibody, autl2 antibody, F6E13.27 antibody, APG4A antibody, zgc:111958 antibody, Aut2a antibody, AUTL2 antibody, AI627006 antibody, AV169859 antibody, Apg4a antibody, Atg4al antibody, Autl2 antibody, Atg4a antibody, autophagy related 4A cysteine peptidase L homeolog antibody, autophagy related 4A cysteine peptidase antibody, Peptidase family C54 protein antibody, ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody, autophagy related 4A, cysteine peptidase antibody, atg4a.L antibody, ATG4A antibody, AT2G44140 antibody, atg4a antibody, Atg4a antibody

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Molecular Weight: 45 kDa

Gene ID: 115201

NCBI Accession: NP_443168

UniProt: Q8WYN0

Pathways: Autophagy