Symplekin antibody

Catalog No. ABIN2458685

Product Details anti-Symplekin Antibody

Target: Symplekin (SYMPK)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Symplekin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SYMPK.

Application Details

Application Notes: SYMPK antibody can be used for detection of SYMPK by ELISA at 1:1562500. SYMPK antibody can be used for detection of SYMPK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SYMPK antibody at -20 °C.

Target Details for Symplekin

Target: Symplekin (SYMPK)

Alternative Name: SYMPK (SYMPK Products)

Synonyms: SPK antibody, SYM antibody, CG2097 antibody, Dmel\\CG2097 antibody, dSymp antibody, 1500016F02Rik antibody, 4632415H16Rik antibody, AA125406 antibody, AI449890 antibody, Hfn3g antibody, sympk antibody, MGC75595 antibody, SYMPK antibody, T22C5.3 antibody, DKFZp468C0711 antibody, symplekin antibody, Symplekin antibody, symplekin S homeolog antibody, SYMPK antibody, Sym antibody, Sympk antibody, sympk.S antibody, sympk antibody, LOC552752 antibody, AT1G27595 antibody, LOC5580150 antibody, CpipJ_CPIJ011126 antibody, Bm1_50390 antibody, NAEGRDRAFT_80124 antibody, LOAG_00841 antibody

Background: SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 141 kDa

Gene ID: 8189

NCBI Accession: NP_004810

UniProt: Q92797