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HERC5 antibody

HERC5 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2458718
  • Target See all HERC5 Antibodies
    HERC5 (Hect Domain and RLD 5 (HERC5))
    Reactivity
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 12
    • 1
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    This HERC5 antibody is un-conjugated
    Application
    • 9
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HERC5.
    Top Product
    Discover our top product HERC5 Primary Antibody
  • Application Notes
    HERC5 antibody can be used for detection of HERC5 by ELISA at 1:312500. HERC5 antibody can be used for detection of HERC5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store HERC5 antibody at -20 °C.
  • Target
    HERC5 (Hect Domain and RLD 5 (HERC5))
    Alternative Name
    HERC5 (HERC5 Products)
    Synonyms
    HERC5 antibody, CEB1 antibody, CEBP1 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antibody, hect domain and RLD 5 antibody, HERC5 antibody
    Background
    HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
    Molecular Weight
    117 kDa
    Gene ID
    51191
    NCBI Accession
    NP_057407
    UniProt
    Q69G20
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