KTN1 antibody

Catalog No. ABIN2458912

Product Details anti-KTN1 Antibody

Target: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KTN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KTN1.

Application Details

Application Notes: KTN1 antibody can be used for detection of KTN1 by ELISA at 1:62500. KTN1 antibody can be used for detection of KTN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KTN1 antibody at -20 °C.

Target Details for KTN1

Target: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Alternative Name: KTN1 (KTN1 Products)

Synonyms: cb213 antibody, wu:fi20e02 antibody, wu:fi27f06 antibody, CG1 antibody, KNT antibody, MU-RMS-40.19 antibody, kinectin 1 antibody, kinectin antibody, kinectin 1 L homeolog antibody, Ktn1 antibody, ktn1 antibody, KTN1 antibody, CpipJ_CPIJ006678 antibody, CpipJ_CPIJ006680 antibody, CpipJ_CPIJ007437 antibody, ktn1.L antibody

Background: Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin, an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.

Molecular Weight: 150 kDa

Gene ID: 3895

NCBI Accession: NP_001072990

UniProt: Q17RZ5