MRPL39 antibody

Catalog No. ABIN2459002

Product Details anti-MRPL39 Antibody

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MRPL39.

Application Details

Application Notes: MRPL39 antibody can be used for detection of MRPL39 by ELISA at 1:312500. MRPL39 antibody can be used for detection of MRPL39 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MRPL39 antibody at -20 °C.

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MRPL39 (MRPL39 Products)

Synonyms: CG17166 antibody, Dmel\\CG17166 antibody, MRP-L5 antibody, mRpL5 antibody, C21orf92 antibody, L39mt antibody, MRPL5 antibody, PRED22 antibody, PRED66 antibody, RPML5 antibody, C21orf8 antibody, ORF22 antibody, Rpml5 antibody, mitochondrial ribosomal protein L39 antibody, mitochondrial ribosomal protein L39 L homeolog antibody, mRpL39 antibody, mrpl39.L antibody, MRPL39 antibody, Mrpl39 antibody

Background: Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL39 is a 39S subunit protein. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Molecular Weight: 39 kDa

Gene ID: 54148

NCBI Accession: NP_059142

UniProt: Q9NYK5