TMEM48 antibody

Catalog No. ABIN2459004

Product Details anti-TMEM48 Antibody

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM48 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM48.

Application Details

Application Notes: TMEM48 antibody can be used for detection of TMEM48 by ELISA at 1:62500. TMEM48 antibody can be used for detection of TMEM48 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMEM48 antibody at -20 °C.

Target Details for TMEM48

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Alternative Name: TMEM48 (TMEM48 Products)

Synonyms: 2810475A17Rik antibody, AI450313 antibody, Tmem48 antibody, NET3 antibody, TMEM48 antibody, tmem48 antibody, wu:fk93f04 antibody, zgc:55636 antibody, Xndr antibody, NDC1 transmembrane nucleoporin antibody, NDC1 transmembrane nucleoporin S homeolog antibody, Xrcc1 N-terminal domain containing 1 antibody, Ndc1 antibody, NDC1 antibody, ndc1 antibody, ndc1.S antibody, Xndc1 antibody

Background: TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.

Molecular Weight: 76 kDa

Gene ID: 55706

NCBI Accession: NP_060557

UniProt: Q9BTX1