CENPM antibody

Catalog No. ABIN2459009

Product Details anti-CENPM Antibody

Target: CENPM (Centromere Protein M (CENPM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CENPM.

Application Details

Application Notes: CENPM antibody can be used for detection of CENPM by ELISA at 1:312500. CENPM antibody can be used for detection of CENPM by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CENPM antibody at -20 °C.

Target Details for CENPM

Target: CENPM (Centromere Protein M (CENPM))

Alternative Name: CENPM (CENPM Products)

Synonyms: C22orf18 antibody, CENP-M antibody, PANE1 antibody, bK250D10.2 antibody, 2610019I03Rik antibody, AI853711 antibody, Pane1 antibody, RGD1307309 antibody, centromere protein M antibody, centromere protein M L homeolog antibody, Centromere protein M antibody, centromere protein M pseudogene antibody, CENPM antibody, Cenpm antibody, cenpm antibody, cenpm.L antibody, LOC100353362 antibody

Background: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).

Molecular Weight: 20 kDa

Gene ID: 79019

NCBI Accession: NP_076958

UniProt: Q9NSP4