PIGQ antibody

Catalog No. ABIN2459019

Product Details anti-PIGQ Antibody

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIGQ.

Application Details

Application Notes: PIGQ antibody can be used for detection of PIGQ by ELISA at 1:312500. PIGQ antibody can be used for detection of PIGQ by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PIGQ antibody at -20 °C.

Target Details for PIGQ

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Alternative Name: PIGQ (PIGQ Products)

Synonyms: GPI1 antibody, c407A10.1 antibody, Gpi1 antibody, Gpi1h antibody, Gpi1p antibody, Gpih antibody, phosphatidylinositol glycan anchor biosynthesis class Q antibody, phosphatidylinositol glycan anchor biosynthesis, class Q antibody, PIGQ antibody, Pigq antibody

Background: PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).

Molecular Weight: 65 kDa

Gene ID: 9091

NCBI Accession: NP_004195

UniProt: B2RAU6

Pathways: Inositol Metabolic Process