IL11RA antibody

Catalog No. ABIN2459023

Product Details anti-IL11RA Antibody

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL11RA.

Application Details

Application Notes: IL11RA antibody can be used for detection of IL11RA by ELISA at 1:12500. IL11RA antibody can be used for detection of IL11RA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IL11RA antibody at -20 °C.

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA (IL11RA Products)

Synonyms: CRSDA antibody, fi26e06 antibody, il-11ra antibody, wu:fi26e06 antibody, AI314697 antibody, GP130 antibody, Il-11ra antibody, Il11ra antibody, Il11ra2 antibody, NR1 antibody, interleukin 11 receptor subunit alpha antibody, interleukin 11 receptor, alpha antibody, interleukin 11 receptor subunit alpha 1 antibody, interleukin 11 receptor, alpha chain 1 antibody, IL11RA antibody, il11ra antibody, Il11ra1 antibody, Il11ra antibody

Background: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

Molecular Weight: 43 kDa

Gene ID: 3590

NCBI Accession: NP_004503

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding