AFG3L2 antibody

Catalog No. ABIN2459048

Product Details anti-AFG3L2 Antibody

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFG3L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AFG3L2.

Application Details

Application Notes: AFG3L2 antibody can be used for detection of AFG3L2 by ELISA at 1:312500. AFG3L2 antibody can be used for detection of AFG3L2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AFG3L2 antibody at -20 °C.

Target Details for AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Alternative Name: AFG3L2 (AFG3L2 Products)

Synonyms: MGC147390 antibody, si:ch211-12e1.4 antibody, SCA28 antibody, SPAX5 antibody, 2310036I02Rik antibody, AW260507 antibody, Emv66 antibody, par antibody, AFG3 like matrix AAA peptidase subunit 2 antibody, AFG3-like protein 2 antibody, AFG3 ATPase family gene 3-like 2 (S. cerevisiae) antibody, AFG3-like AAA ATPase 2 antibody, AFG3-like AAA ATPase 2 L homeolog antibody, AFG3L2 antibody, LOC578526 antibody, afg3l2 antibody, afg3l2.L antibody, Afg3l2 antibody

Background: AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

Molecular Weight: 88 kDa

Gene ID: 10939

NCBI Accession: NP_006787

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development