PCDH12 antibody

Catalog No. ABIN2459088

Product Details anti-PCDH12 Antibody

Target: PCDH12 (Protocadherin 12 (PCDH12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDH12.

Application Details

Application Notes: PCDH12 antibody can be used for detection of PCDH12 by ELISA at 1:312500. PCDH12 antibody can be used for detection of PCDH12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDH12 antibody at -20 °C.

Target Details for PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Alternative Name: PCDH12 (PCDH12 Products)

Synonyms: PCDH12 antibody, VE-cadherin-2 antibody, VECAD2 antibody, Pcdh14 antibody, VE-cad-2 antibody, protocadherin 12 antibody, PCDH12 antibody, Pcdh12 antibody

Background: PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.

Molecular Weight: 126 kDa

Gene ID: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process