ADCY10 antibody

Catalog No. ABIN2459117

Product Details anti-ADCY10 Antibody

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAC.

Application Details

Application Notes: SAC antibody can be used for detection of SAC by ELISA at 1:62500. SAC antibody can be used for detection of SAC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAC antibody at -20 °C.

Target Details for ADCY10

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Alternative Name: SAC (ADCY10 Products)

Synonyms: HCA2 antibody, RP1-313L4.2 antibody, SAC antibody, SACI antibody, Sacy antibody, Sac antibody, 4930431D04Rik antibody, 4931412F17 antibody, sAC antibody, ADCY10 antibody, SACY antibody, adenylate cyclase 10 antibody, adenylate cyclase 10 (soluble) antibody, ADCY10 antibody, Adcy10 antibody

Background: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 187 kDa

Gene ID: 55811

NCBI Accession: NP_060887

UniProt: Q96PN6

Pathways: cAMP Metabolic Process