GBAS antibody

Catalog No. ABIN2459174

Product Details anti-GBAS Antibody

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GBAS.

Application Details

Application Notes: GBAS antibody can be used for detection of GBAS by ELISA at 1:12500. GBAS antibody can be used for detection of GBAS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GBAS antibody at -20 °C.

Target Details for GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Alternative Name: GBAS (GBAS Products)

Synonyms: nipsnap2 antibody, wu:fc08b08 antibody, zgc:92497 antibody, NIPSNAP2 antibody, AV006093 antibody, Nipsnap2 antibody, nipsnap homolog 2 antibody, glioblastoma amplified sequence antibody, nipsnap2 antibody, NIPSNAP2 antibody, GBAS antibody, Nipsnap2 antibody

Background: Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.

Molecular Weight: 34 kDa

Gene ID: 2631

NCBI Accession: NP_001474

UniProt: O75323

Pathways: Ribonucleoside Biosynthetic Process