CMAS antibody

Catalog No. ABIN2459239

Product Details anti-CMAS Antibody

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CMAS.

Application Details

Application Notes: CMAS antibody can be used for detection of CMAS by ELISA at 1:12500. CMAS antibody can be used for detection of CMAS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CMAS antibody at -20 °C.

Target Details for CMAS

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Alternative Name: CMAS (CMAS Products)

Synonyms: CSS antibody, cmas antibody, cmas1 antibody, si:dkey-183c2.1 antibody, wu:fj16c12 antibody, zgc:136241 antibody, AW208911 antibody, CMPNeu5Ac antibody, D6Bwg0250e antibody, cytidine monophosphate N-acetylneuraminic acid synthetase antibody, cytidine monophosphate N-acetylneuraminic acid synthetase a antibody, cytidine monophospho-N-acetylneuraminic acid synthetase antibody, CMAS antibody, Cmas antibody, cmasa antibody, cmas antibody

Background: CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.

Molecular Weight: 48 kDa

Gene ID: 55907

NCBI Accession: NP_061156

UniProt: Q8NFW8