QTRT1 antibody

Catalog No. ABIN2459249

Product Details anti-QTRT1 Antibody

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QTRT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human QTRT1.

Application Details

Application Notes: QTRT1 antibody can be used for detection of QTRT1 by ELISA at 1:62500. QTRT1 antibody can be used for detection of QTRT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store QTRT1 antibody at -20 °C.

Target Details for QTRT1

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Alternative Name: QTRT1 (QTRT1 Products)

Synonyms: CG4947 antibody, Dmel\\CG4947 antibody, TGT antibody, tgt antibody, zgc:66378 antibody, FP3235 antibody, TGUT antibody, 2610028E17Rik antibody, Tgt antibody, Tgut antibody, tRNA-guanine transglycosylase antibody, queuine tRNA-ribosyltransferase 1 S homeolog antibody, queuine tRNA-ribosyltransferase 1 antibody, queuine tRNA-ribosyltransferase catalytic subunit 1 antibody, Tgt antibody, Olsu_0732 antibody, Palpr_1298 antibody, Riean_1227 antibody, Calni_1240 antibody, Ftrac_0312 antibody, Ocepr_1541 antibody, Sulku_0977 antibody, Tmar_0854 antibody, Bache_2323 antibody, Nitsa_1291 antibody, Isop_1657 antibody, Despr_0021 antibody, Pedsa_1842 antibody, Corgl_1148 antibody, Mahau_0921 antibody, Theth_0831 antibody, qtrt1.S antibody, qtrt1 antibody, QTRT1 antibody, Qtrt1 antibody

Background: TRNA-guanine transglycosylase (TGT, EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14, MIM 607274) and a 43-kD catalytic subunit (QTRT1). tRNA-guanine transglycosylase (TGT, EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14, MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]).

Molecular Weight: 44 kDa

Gene ID: 81890

NCBI Accession: NP_112486

UniProt: Q80VS3

Pathways: Ribonucleoside Biosynthetic Process