EDAR antibody
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- Target See all EDAR Antibodies
- EDAR (Ectodysplasin A Receptor (EDAR))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EDAR antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDAR.
- Top Product
- Discover our top product EDAR Primary Antibody
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- Application Notes
- EDAR antibody can be used for detection of EDAR by ELISA at 1:12500. EDAR antibody can be used for detection of EDAR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store EDAR antibody at -20 °C.
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- Target
- EDAR (Ectodysplasin A Receptor (EDAR))
- Alternative Name
- EDAR (EDAR Products)
- Synonyms
- rs3 antibody, edar antibody, EDAR antibody, MGC88893 antibody, DL antibody, ECTD10A antibody, ECTD10B antibody, ED1R antibody, ED3 antibody, ED5 antibody, EDA-A1R antibody, EDA1R antibody, EDA3 antibody, HRM1 antibody, dl antibody, RGD1561714 antibody, ectodysplasin A receptor antibody, ectodysplasin-A receptor antibody, edar antibody, EDAR antibody, Edar antibody
- Background
- EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Molecular Weight
- 48 kDa
- Gene ID
- 10913
- NCBI Accession
- NP_071731
- UniProt
- Q9UNE0
- Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
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