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PCDHA3 antibody

PCDHA3 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2459348
  • Target See all PCDHA3 Antibodies
    PCDHA3 (Protocadherin alpha 3 (PCDHA3))
    Reactivity
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHA3 antibody is un-conjugated
    Application
    • 22
    • 16
    • 16
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA3.
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    Discover our top product PCDHA3 Primary Antibody
  • Application Notes
    PCDHA3 antibody can be used for detection of PCDHA3 by ELISA at 1:62500. PCDHA3 antibody can be used for detection of PCDHA3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHA3 antibody at -20 °C.
  • Target
    PCDHA3 (Protocadherin alpha 3 (PCDHA3))
    Alternative Name
    PCDHA3 (PCDHA3 Products)
    Synonyms
    PCDH-ALPHA3 antibody, mKIAA0345 antibody, PCDHA2 antibody, PCDHA3 antibody, PCDHA4 antibody, Pcdha3 antibody, protocadherin alpha 3 antibody, protocadherin alpha-3 antibody, PCDHA3 antibody, Pcdha3 antibody, pcdha3 antibody, LOC100713314 antibody
    Background
    PCDHA3 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Molecular Weight
    99 kDa
    Gene ID
    56145
    NCBI Accession
    NP_061729
    UniProt
    Q9Y5H8
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