PIGO antibody

Catalog No. ABIN2459357

Product Details anti-PIGO Antibody

Target: PIGO (Phosphatidylinositol Glycan Anchor Biosynthesis, Class O (PIGO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGO antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIGO.

Application Details

Application Notes: PIGO antibody can be used for detection of PIGO by ELISA at 1:1562500. PIGO antibody can be used for detection of PIGO by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PIGO antibody at -20 °C.

Target Details for PIGO

Target: PIGO (Phosphatidylinositol Glycan Anchor Biosynthesis, Class O (PIGO))

Alternative Name: PIGO (PIGO Products)

Synonyms: HPMRS2 antibody, RP11-182N22.4 antibody, mFLJ00350 antibody, phosphatidylinositol glycan anchor biosynthesis class O antibody, phosphatidylinositol glycan anchor biosynthesis, class O antibody, PIGO antibody, Pigo antibody

Background: PIGO is a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGO is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI.This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.

Molecular Weight: 74 kDa

Gene ID: 84720

NCBI Accession: NP_690577

UniProt: B1AML3

Pathways: Inositol Metabolic Process, SARS-CoV-2 Protein Interactome