FCRLA antibody

Catalog No. ABIN2459358

Product Details anti-FCRLA Antibody

Target: FCRLA (Fc Receptor-Like A (FCRLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCRLA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FCRLA.

Application Details

Application Notes: FCRLA antibody can be used for detection of FCRLA by ELISA at 1:62500. FCRLA antibody can be used for detection of FCRLA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FCRLA antibody at -20 °C.

Target Details for FCRLA

Target: FCRLA (Fc Receptor-Like A (FCRLA))

Alternative Name: FCRLA (FCRLA Products)

Synonyms: FCRL antibody, FCRL1 antibody, FCRLM1 antibody, FCRLX antibody, FCRLb antibody, FCRLc1 antibody, FCRLc2 antibody, FCRLd antibody, FCRLe antibody, FCRX antibody, FREB antibody, BB219290 antibody, Fcrlm1 antibody, Fcrx antibody, Freb1 antibody, mFREB antibody, mFcrX antibody, RGD1306176 antibody, Fc receptor like A antibody, Fc receptor-like A antibody, FCRLA antibody, Fcrla antibody

Background: Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.

Molecular Weight: 41 kDa

Gene ID: 84824

NCBI Accession: NP_116127

UniProt: Q7L513