BRI3BP antibody

Catalog No. ABIN2459386

Product Details anti-BRI3BP Antibody

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRI3BP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BRI3BP.

Application Details

Application Notes: BRI3BP antibody can be used for detection of BRI3BP by ELISA at 1:1562500. BRI3BP antibody can be used for detection of BRI3BP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BRI3BP antibody at -20 °C.

Target Details for BRI3BP

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Alternative Name: BRI3BP (BRI3BP Products)

Synonyms: fa20c12 antibody, wu:fa20c12 antibody, kg19 antibody, bnas1 antibody, hccr-2 antibody, BNAS1 antibody, HCCR-1 antibody, HCCR-2 antibody, HCCRBP-1 antibody, KG19 antibody, 2410150I18Rik antibody, AI841257 antibody, AW742481 antibody, bri3 binding protein antibody, BRI3 binding protein pseudogene antibody, BRI3 binding protein L homeolog antibody, BRI3 binding protein antibody, Bri3 binding protein antibody, bri3bp antibody, LOC452360 antibody, bri3bp.L antibody, BRI3BP antibody, Bri3bp antibody

Background: BRI3BP is involved in the structural dynamics of the ER and affects mitochondrial viability.It is widely expressed in animal cell types, that seems to possess a pro-apoptotic property and can potentiate drug-induced apoptosis.The protein is highly expressed in brain, kidney, and liver, and it mapped to human chromosome 12q24.2-qter.Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).

Molecular Weight: 28 kDa

Gene ID: 140707

NCBI Accession: NP_542193

UniProt: Q8WY22