DCP1B antibody

Catalog No. ABIN2459448

Product Details anti-DCP1B Antibody

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCP1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP1B.

Application Details

Application Notes: DCP1B antibody can be used for detection of DCP1B by ELISA at 1:62500. DCP1B antibody can be used for detection of DCP1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DCP1B antibody at -20 °C.

Target Details for DCP1B

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Alternative Name: DCP1B (DCP1B Products)

Synonyms: DCP1 antibody, hDcp1b antibody, B930050E02Rik antibody, RGD1562214 antibody, dcp1 antibody, dcp1b antibody, mitc1l antibody, si:ch211-87p6none antibody, decapping mRNA 1B antibody, decapping mRNA 1B L homeolog antibody, DCP1B antibody, Dcp1b antibody, dcp1b.L antibody, dcp1b antibody

Background: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).

Molecular Weight: 68 kDa

Gene ID: 196513

NCBI Accession: NP_689853

UniProt: Q8IZD4