EXOC3 antibody

Catalog No. ABIN2459523

Product Details anti-EXOC3 Antibody

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EXOC3.

Application Details

Application Notes: EXOC3 antibody can be used for detection of EXOC3 by ELISA at 1:312500. EXOC3 antibody can be used for detection of EXOC3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EXOC3 antibody at -20 °C.

Target Details for EXOC3

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Alternative Name: EXOC3 (EXOC3 Products)

Synonyms: CG5341 antibody, Dmel\\CG5341 antibody, Dsec6 antibody, Sec6 antibody, Sec6p antibody, dsec6 antibody, sec 6 antibody, F14O23.20 antibody, F14O23_20 antibody, sec6l1 antibody, fi26g09 antibody, wu:fi26g09 antibody, wu:fi34a09 antibody, wu:fj62h05 antibody, wu:fk66f08 antibody, zgc:55709 antibody, SEC6L1 antibody, SEC6 antibody, 2810050O03Rik antibody, E430013E20Rik antibody, Sec6l1 antibody, rSec6 antibody, Secretory 6 antibody, SEC6 antibody, exocyst complex component 3 antibody, Exocyst complex component 3 antibody, Sec6 antibody, SEC6 antibody, EXOC3 antibody, exoc3 antibody, Exoc3 antibody, sec-6 antibody

Background: EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Molecular Weight: 85 kDa

Gene ID: 11336

NCBI Accession: NP_009208

UniProt: Q6P2E8

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis