ENPP6 antibody

Catalog No. ABIN2459637

Product Details anti-ENPP6 Antibody

Target: ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ENPP6.

Application Details

Application Notes: ENPP6 antibody can be used for detection of ENPP6 by ELISA at 1:1562500. ENPP6 antibody can be used for detection of ENPP6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ENPP6 antibody at -20 °C.

Target Details for ENPP6

Target: ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

Alternative Name: ENPP6 (ENPP6 Products)

Synonyms: E-NPP 6 antibody, cb1028 antibody, sb:cb727 antibody, zgc:103605 antibody, NPP6 antibody, NPP-6 antibody, 4833421B01Rik antibody, B830047L21Rik antibody, D8Ertd514e antibody, Npp6 antibody, E-NPP6 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 6 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 6 L homeolog antibody, enpp6 antibody, enpp6.L antibody, ENPP6 antibody, Enpp6 antibody

Background: ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.

Molecular Weight: 50 kDa

Gene ID: 133121

NCBI Accession: NP_699174

UniProt: Q6UWR7