STAMBP antibody

Catalog No. ABIN2459686

Product Details anti-STAMBP Antibody

Target: STAMBP (STAM Binding Protein (STAMBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAMBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAMBP.

Application Details

Application Notes: STAMBP antibody can be used for detection of STAMBP by ELISA at 1:312500. STAMBP antibody can be used for detection of STAMBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store STAMBP antibody at -20 °C.

Target Details for STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Alternative Name: STAMBP (STAMBP Products)

Synonyms: AMSH antibody, 5330424L14Rik antibody, 5730422L11Rik antibody, AW107289 antibody, Amsh antibody, mKIAA4198 antibody, stambp antibody, zgc:66147 antibody, STAM binding protein antibody, Stam binding protein antibody, STAM binding protein a antibody, STAMBP antibody, Stambp antibody, stambpa antibody

Background: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Molecular Weight: 48 kDa

Gene ID: 10617

NCBI Accession: NP_998787

UniProt: O95630