CHRNG antibody

Catalog No. ABIN2460108

Product Details anti-CHRNG Antibody

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNG.

Application Details

Application Notes: CHRNG antibody can be used for detection of CHRNG by ELISA at 1:312500. CHRNG antibody can be used for detection of CHRNG by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHRNG antibody at -20 °C.

Target Details for CHRNG

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Alternative Name: CHRNG (CHRNG Products)

Synonyms: ACHRG antibody, Achr-3 antibody, Acrg antibody, cholinergic receptor nicotinic gamma subunit antibody, cholinergic receptor, nicotinic gamma L homeolog antibody, cholinergic receptor, nicotinic, gamma antibody, cholinergic receptor, nicotinic gamma antibody, cholinergic receptor, nicotinic, gamma polypeptide antibody, CHRNG antibody, chrng.L antibody, Chrng antibody, chrng antibody

Background: For background information on the acetylcholine receptor (AChR), see CHRNA1. Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit, which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity.For background information on the acetylcholine receptor (AChR), see CHRNA1 (MIM 100690). Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit (MIM 100725), which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity, MIM 142445).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2187 AK125362.1 1-2187

Molecular Weight: 56 kDa

Gene ID: 1146

NCBI Accession: NP_005190

UniProt: P07510