DEK antibody

Catalog No. ABIN2460117

Product Details anti-DEK Antibody

Target: DEK (DEK Oncogene (DEK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEK.

Application Details

Application Notes: DEK antibody can be used for detection of DEK by ELISA at 1:1562500. DEK antibody can be used for detection of DEK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DEK antibody at -20 °C.

Target Details for DEK

Target: DEK (DEK Oncogene (DEK))

Alternative Name: DEK (DEK Products)

Synonyms: D6S231E antibody, DEK antibody, 1810019E15Rik antibody, D13H6S231E antibody, DEK proto-oncogene antibody, DEK proto-oncogene L homeolog antibody, DEK oncogene (DNA binding) antibody, DEK oncogene antibody, DEK antibody, Dek antibody, dek.L antibody, LOC398543 antibody

Background: DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 43 kDa

Gene ID: 7913

NCBI Accession: NP_003463

UniProt: P35659