TRIM22 antibody

Catalog No. ABIN2460132

Product Details anti-TRIM22 Antibody

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM22.

Application Details

Application Notes: TRIM22 antibody can be used for detection of TRIM22 by ELISA at 1:312500. TRIM22 antibody can be used for detection of TRIM22 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIM22 antibody at -20 °C.

Target Details for TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Alternative Name: TRIM22 (TRIM22 Products)

Synonyms: GPSTAF50 antibody, RNF94 antibody, STAF50 antibody, tripartite motif containing 22 antibody, TRIM22 antibody

Background: TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 57 kDa

Gene ID: 10346

NCBI Accession: NP_006065

UniProt: Q8IYM9