PSMD11 antibody

Catalog No. ABIN2460432

Product Details anti-PSMD11 Antibody

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMD11.

Application Details

Application Notes: PSMD11 antibody can be used for detection of PSMD11 by ELISA at 1:312500. PSMD11 antibody can be used for detection of PSMD11 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMD11 antibody at -20 °C.

Target Details for PSMD11

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Alternative Name: PSMD11 (PSMD11 Products)

Synonyms: psmd11 antibody, wu:fb55b06 antibody, zgc:56580 antibody, zgc:77763 antibody, Rpn6 antibody, S9 antibody, p44.5 antibody, 1700089D09Rik antibody, 1810019E17Rik antibody, 2610024G20Rik antibody, 2810055C24Rik antibody, C78232 antibody, P44.5 antibody, proteasome 26S subunit, non-ATPase 11 antibody, proteasome 26S subunit, non-ATPase 11b antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, PSMD11 antibody, psmd11b antibody, Psmd11 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 47 kDa

Gene ID: 5717

NCBI Accession: NP_002806

UniProt: O00231

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway