SND1 antibody

Catalog No. ABIN2460503

Product Details anti-SND1 Antibody

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SND1.

Application Details

Application Notes: SND1 antibody can be used for detection of SND1 by ELISA at 1:62500. SND1 antibody can be used for detection of SND1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SND1 antibody at -20 °C.

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1 (SND1 Products)

Synonyms: P100 antibody, TDRD11 antibody, p100 antibody, AL033314 antibody, SND p102 antibody, snd1 antibody, tdrd11 antibody, SN4TDR antibody, fc27g10 antibody, p100L antibody, p100S antibody, wu:fc27g10 antibody, staphylococcal nuclease and tudor domain containing antibody, staphylococcal nuclease and tudor domain containing 1 antibody, staphylococcal nuclease and tudor domain containing protein 1 S homeolog antibody, SND1 antibody, Snd1 antibody, snd1.S antibody, snd1 antibody

Background: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

Molecular Weight: 100 kDa

Gene ID: 27044

NCBI Accession: NP_055205

UniProt: Q7KZF4