PSMD11 antibody
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- Target See all PSMD11 Antibodies
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
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Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD11 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMD11.
- Top Product
- Discover our top product PSMD11 Primary Antibody
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- Application Notes
- PSMD11 antibody can be used for detection of PSMD11 by ELISA at 1:312500. PSMD11 antibody can be used for detection of PSMD11 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMD11 antibody at -20 °C.
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- Target
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
- Alternative Name
- PSMD11 (PSMD11 Products)
- Synonyms
- psmd11 antibody, wu:fb55b06 antibody, zgc:56580 antibody, zgc:77763 antibody, Rpn6 antibody, S9 antibody, p44.5 antibody, 1700089D09Rik antibody, 1810019E17Rik antibody, 2610024G20Rik antibody, 2810055C24Rik antibody, C78232 antibody, P44.5 antibody, proteasome 26S subunit, non-ATPase 11 antibody, proteasome 26S subunit, non-ATPase 11b antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, PSMD11 antibody, psmd11b antibody, Psmd11 antibody
- Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
- Molecular Weight
- 47 kDa
- Gene ID
- 5717
- NCBI Accession
- NP_002806
- UniProt
- O00231
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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