PCYOX1 antibody

Catalog No. ABIN2460634

Product Details anti-PCYOX1 Antibody

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCYOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCYOX1.

Application Details

Application Notes: PCYOX1 antibody can be used for detection of PCYOX1 by ELISA at 1:12500. PCYOX1 antibody can be used for detection of PCYOX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCYOX1 antibody at -20 °C.

Target Details for PCYOX1

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Alternative Name: PCYOX1 (PCYOX1 Products)

Synonyms: PCL1 antibody, 1200015P13Rik antibody, AI115532 antibody, AI448340 antibody, Pcly antibody, Clp55 antibody, pcl1 antibody, zgc:110246 antibody, prenylcysteine oxidase 1 antibody, PCYOX1 antibody, Pcyox1 antibody, pcyox1 antibody

Background: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

Molecular Weight: 57 kDa

Gene ID: 51449

NCBI Accession: NP_057381

UniProt: Q9UHG3