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POU4F3 antibody

POU4F3 Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio) WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2460646
  • Target See all POU4F3 Antibodies
    POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
    Reactivity
    • 28
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)
    Host
    • 21
    • 6
    • 1
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POU4F3 antibody is un-conjugated
    Application
    • 19
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.
    Top Product
    Discover our top product POU4F3 Primary Antibody
  • Application Notes
    POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.
  • Target
    POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
    Alternative Name
    POU4F3 (POU4F3 Products)
    Synonyms
    POU4F3 antibody, BRN-3 antibody, BRN3 antibody, BRN3C antibody, DFNA15 antibody, BRN-3.1 antibody, brn-3c antibody, brn3.1 antibody, brn3c antibody, Brn3.1 antibody, Brn3c antibody, ddl antibody, dreidel antibody, POU class 4 homeobox 3 antibody, POU domain, class 4, transcription factor 3 antibody, POU4F3 antibody, Pou4f3 antibody, pou4f3 antibody
    Background
    POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
    Molecular Weight
    37 kDa
    Gene ID
    5459
    NCBI Accession
    NP_002691
    UniProt
    Q15319
    Pathways
    Sensory Perception of Sound
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